A copper toned publication!

At long last (1.5yrs since the first submission attempt to be exact), the research I worked on as a post-doctoral fellow has been published!

Click on the image above to head over to the article for some light reading.  A lot of work went into this paper, and there are many to thank who don't appear in the author list - basically everyone in my former lab. On a fun note, the model we developed and just about all the figures were produced in R.  Quite the conversion, since I started this work as a big proponent for Matlab.

Interesting references

These have been languishing in a Google Doc for some time (Aug 2009 to be exact).  Perhaps having them here might help me to read them more carefully ...

Influence of Heavy Metals on Microbial Growth Kinetics Including Lag Time: Mathematical Modeling and Experimental Verification.

PMID: 19496634.  This looks like an interesting model to study - esp given the specific ways Zn and Cu affect halo growth

Also,

Removal of multi-heavy metals using biogenic manganese oxides generated by a deep-sea sedimentary bacterium - Brachybacterium sp. strain Mn32.

PMID: 19383675.  Apparently oxides of Mn(II) can sequester Zn, maybe copper.  Check to see how Mn(II) specific resistance is differentially expression during Zn/Cu stress.

Oh, hell yes ...

A P-type ATPase importer that discriminates between essential and toxic transition metals.

PMID: 19264958.  A heavy metal importer with specificity to Cu and Zn is identified in Pseudomonas aeruginosa Q9I147.  There are several importers described or referenced here with specificities only for Cu or Zn.  Get protein sequences and blast against the Halo proteome.

Last, worthwhile to review.  I might have this one already

The role of efflux in bacterial resistance to soft metals and metalloids.

PMID: 10730185